Summary: Doxorubicin induces myocardial injury and fibrosis.Still, no effective interventions are available.AP39 is an H2S donor that explicitly targets mitochondria.This study investigated whether AP39 could improve doxorubicin-induced myocardial fibrosis.Doxorubicin induced significant myocardial fibrosis while suppressing mitophagy-related prote
Alexandra Enocson, Kate Jolly, Rachel Elizabeth Jordan, David A Denture Care Fitzmaurice, SM Greenfield, Peymane Adab On behalf of the BLISS research team Institute of Applied Health Research, University of Birmingham, Edgbaston, Birmingham, West Midlands, UK Background: COPD is a leading cause of morbidity and mortality, yet it remains largely und
Recent studies suggested significant impacts of boreal cryosphere changes on wintertime air stagnation and haze pollution extremes in China.However, the underlying mechanisms of such a teleconnection relationship remains unclear.Here we use the Whole Atmosphere Community Climate Model (WACCM) to investigate dynamic processes leading to atmospheric
Background and Desk Chair Objectives: Climate phenomena such as quantity of surface evaporation are affected by many environmental factors and parameters, which makes modeling and data mining difficult.On the other hand, the estimation of surface evaporation for a target station can be difficult as a result of partial or complete lack of local mete
The study investigated the information and training sources used by rice farmers in North central, Nigeria.A total of 320 respondents were selected and interviewed using structured interview schedule.The respondents were of two categories, the participants and non-participants of the intervention programme.The data were analyzed using frequency, pe